The DNA repair enzyme, apurinic/apyrimidinic endonuclease (or redox effector factor-1, APE/Ref-1), is involved in base excision repair of apurinic/apyrimidinic sites after oxidative DNA damage.We investigated the expression of APE/Ref-1 and its relationship to oxidative stress after severe traumatic brain injury produced by controlled cortical impa

Expression of oncogenic KrasG12D initiates lung adenomas in a mitogen-activated protein kinase (MAPK) signal-dependent manner from only a subset of cell types in the adult mouse lung.Amplification of MAPK signaling is associated with progression to malignant adenocarcinomas, Bead Cord but whether this is a cause or a consequence of disease progress

Purpose: This manuscript explores the link between Spare Parts Management and Total Costs of Ownership or Life Cycle Costs (LCC).Design/methodology/approach: First, this work enumerates the different managerial decisions instances in spare parts management that are present during the life cycle of a physical asset.Second, we analyse how those decis

ABSTRACT Gram-negative bacteria have an outer membrane (OM) impermeable to many toxic compounds that can be further strengthened during stress.In Enterobacteriaceae, the envelope contains enterobacterial common antigen (ECA), a carbohydrate-derived moiety conserved throughout Enterobacteriaceae, the function of which is poorly understood.Previously

The complexity of a sustainable economy is rooted in its Medical Tape socio-economic and environmental intricacies, particularly in formulating pathways for the harmonious integration of these parameters.This study introduces an extended input-output analysis and a multi-objective optimisation framework designed to discern trajectories for reducing